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Year : 2019  |  Volume : 8  |  Issue : 4  |  Page : 222-226

Detection of serum levels of Vitamin C, D, and E in neonatal jaundice

1 Department of Pediatrics, Faculty of Medicine, Tanta University, Tanta, El-Gharbia, Egypt
2 Departments of Clinical Pathology, Tanta University, Tanta, El-Gharbia, Egypt
3 Departments of Biochemistry, Tanta University, Tanta, El-Gharbia, Egypt
4 Department of Nutritional Pediatrics, Al-Azhar University, New Damietta, Egypt

Correspondence Address:
Dr. Mohamed Shawky Elfarargy
Assistant Professor of Pediatrics and Neonatology, Faculty of Medicine, Tanta University, Tanta, El-Gharbia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcn.JCN_36_19

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Background: Neonatal jaundice is a large problem in the neonates causing many complications in the newborn that need further studies on this common problem. Patients and Methods: This study is considered a case–control study which was done in the neonatal unit of Tanta University Hospital from May 2016 to March 2018. It was done on 100 full-term neonates. A study group which includes 50 neonates admitted in the neonatal unit as they are diagnosed with neonatal jaundice with their bilirubin levels ranging from 15 to 19 mg/dl and 50 healthy outpatient neonates act as a control group. We detect the serum levels of Vitamin C, D, and E in both groups. Results: Serum levels of Vitamin C, D, and E were significantly lower in the study group which include the cases of neonatal jaundice if compared their levels in the control healthy group with negative statistically significant correlation which is present between the serum levels of the bilirubin and the serum levels of Vitamin C, D, and E in the study group. Conclusion: The results of this study revealed that low serum levels of Vitamins C, D, and E are present in neonatal jaundice group indicating that neonatal jaundice is accompanied by decrease the serum levels of these vitamins attracting the attention of the researchers to study the effect of these vitamin supplementations as an adjuvant therapy in neonatal jaundice.

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